HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dimethyl-1H-pyrazole-1-carboxamidine mononitrate → HCID 178512799, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dimethyl-1H-pyrazole-1-carboxamidine mononitrate | HCID 198186 | — |
| Reactant | 8-Amino-2E-octenoic acid trifluoroacetate salt | HCID 86744956 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Solvent | Diisopropylethylamine | HCID 81531 | — |
| Product | HCID 178512799 | HCID 178512799 | 84.3% |
Reaction Steps
A suspension of 21 g (77.4 mmoles) of (10) and 31.1 g (155 mmoles) 3,5-dimethylpyrazole-1carboxamidine nitrate in 50 mL dioxane, 2 mL water and 47.2 mL N,N-diisopropylethylamine was warmed on a steam bath until a clear solution was obtained. After stirring 20 h at room temperature, the solid was filtered and washed well with water to provide 13 g of crude title compound (11).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05037808 |
| Source dataset | uspto-grants-1991_08 |
| ORD ID | ord-41e16604a4b94c5bba0fec06e91a7e09 |
| Source note | uspto-grants-1991_08 |