HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → 2-Methyl-3-(2-morpholinoethylcarbamoyl)-6-(3-nitrophenyl)-4-phenylpyridine dihydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | 1-(3-Nitrophenyl)-3-phenyl-2-propen-1-one | HCID 302446 | — |
| Edukt | Ammonium Acetate | HCID 517165 | — |
| Edukt | N-(2-morpholin-4-ylethyl)-3-oxobutanamide | HCID 4076516 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 2-Methyl-3-(2-morpholinoethylcarbamoyl)-6-(3-nitrophenyl)-4-phenylpyridine dihydrochloride | HCID 67926388 | — |
Reaktionsschritte
2-Methyl-3-(2-morpholinoethylcarbamoyl)-6- 3-nitrophenyl)-4-phenylpyridine, which was obtained according to a similar manner to that of Example 1 from 1-(3-nitrophenyl)-3-phenyl-2-propen-1-one (3.8 g), N-(2-morpholinoethyl)acetoacetamide (5.8 g) and ammonium acetate (2.0 g), was treated with a solution of hydrogen chloride in methanol to give 2-methyl-3-(2-morpholinoethylcarbamoyl)-6-(3-nitrophenyl)-4-phenylpyridine dihydrochloride (1.92 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05037824 |
| Quelldatensatz | uspto-grants-1991_08 |
| ORD ID | ord-a18c357de71946848757b919118e0a47 |
| Quellennotiz | uspto-grants-1991_08 |