HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → HCID 136037530, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 757238-43-0 | HCID 135800570 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 136037530 | HCID 136037530 | 100% |
Reaction Steps
A mixture of 4 parts of intermediate 38, namely 6-(hydroxyphenylmethyl)-4(3H)-quinazolinone, and 67.7 parts of a solution of hydrobromic acid in acetic acid 30% was stirred for 24 hours at room temperature. The reaction mixture was evaporated and the residue was co-evaporated with methylbenzene, yielding 6.5 parts (100%) of 6-(bromophenylmethyl)-4(3H)-quinazolinone monohydrobromide (interm. 48).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05037829 |
| Source dataset | uspto-grants-1991_08 |
| ORD ID | ord-8889431b586845bebf08e7c757a1f8b3 |
| Source note | uspto-grants-1991_08 |