Aniline → HCID 44269396, compound

HRID 224798Notes

Reaction equation

[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:8][C:9]1[N:10]=[C:11]2[CH2:22][CH2:21][CH2:20][CH:19]([CH3:23])[N:12]2[C:13](=[O:18])[C:14]=1[C:15]([NH2:17])=[O:16].C[N:25](C)C=O>>[C:2]1([NH:1][N:25]=[C:22]2[C:11]3=[N:10][C:9]([CH3:8])=[C:14]([C:15]([NH2:17])=[O:16])[C:13](=[O:18])[N:12]3[CH:19]([CH3:23])[CH2:20][CH2:21]2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 3

HCID 6115Aniline

HCID 6228Dimethylformamide

HCID 20452142HCID 20452142, compound

Product 1

HCID 44269396HCID 44269396, compoundYield 49.2%

Procedure

The process according to Example 6 is carried out with the difference that aniline and dimethylformamide solution of 2,6-dimethyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido(1,2-a)pyrimidine-3-carboxamide is used. The crude 9-(phenyl-hydrazono)-2,6-dimethyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido(1,2-a)pyrimidine-3-carboxamide melts at 235°-237° C., yield: 49.2%.

Sources & evidence

ORD record: ord-60787d6b963846db95ec206683216ad9
Source dataset: uspto-grants-1980_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04234586

Reaction notes

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