Isopropyl isocyanate → HCID 14799077, compound

Participants

Reaction Conditions

Reaction Steps

1.9 g. 2-Amino-2-methyl-N-(2-nitroxyethyl)-propionic acid amide is dissolved in 10 ml. ethyl acetate and mixed with 1.1 ml. isopropyl isocyanate while cooling with ice-water to 5° to 10° C. The reaction mixture is stirred for 2 hours at 10° C., filtered off with suction and washed with diethyl ether. There is obtained 1.4 g. of the title compound, i.e. 50% of theory; m.p. 120°-122° C.

Provenance & Evidence