Ammonia → HCID 178511445, compound

Participants

Reaction Steps

11.5 g. (0.06 mole) trans-2-chloro-N-(4-hydroxycyclohexyl)-acetamide are dissolved in 100 ml. methanol and shaken with 200 ml. liquid ammonia for 20 hours at 50° C. in an autoclave. After concentration of the solvent, suction filtration is carried out. There are obtained 9.7 g. of the title compound, i.e. 94% of theory; m.p. 110°-114° C.

Provenance & Evidence