Sodium Sulfate → 6,12-Dioxaheptadecylamine

HRID 2248046Notes

Reaction equation

HRID 2248046 reaction equation
[H-].[Al+3].[Li+].[H-].[H-].[H-].[C:7](#[N:24])[CH2:8][CH2:9][CH2:10][CH2:11][O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][O:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23].S([O-])([O-])(=O)=O.[Na+].[Na+]>O1CCCC1>[CH2:7]([NH2:24])[CH2:8][CH2:9][CH2:10][CH2:11][O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][O:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23]

Participants

5

Reactant 3

HCID 24436Sodium SulfateHCID 190000196,12-DioxaheptadecanenitrileHCID 21226445Aluminium lithium hydride

Product 1

HCID 189999906,12-DioxaheptadecylamineYield 29.5%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

0.15 g of lithium aluminum hydride was added to a solution of 1 g of 6,12-dioxaheptadecanenitrile prepared in the above-described step (2) in 20 ml of tetrahydrofuran and the mixture was stirred at room temperature for 1.5 h. A saturated aqueous solution of sodium sulfate was added thereto and the obtained mixture was filtered through a Celite filter (eluent: chloroform/methanol=9/1) to obtain 0.3 g of the intended product.

Workup

  1. filtrationthe obtained mixture was filtered through a Celite
  2. filtrationfilter (eluent: chloroform/methanol=9/1)

Sources & evidence

ORD record
ord-2bb200182f454929bb5ae00ec5765498
Source dataset
uspto-grants-1991_08
Patent number
US05037827

Reaction notes

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