Hydrochloric Acid → 2-(1-Isopropyl-3-methyl-5-pyrazolyl) amino-2-imidazoline

HRID 224808Notes

Reaction equation

HRID 224808 reaction equation
C([N:4]1[CH2:8][CH2:7][N:6]=[C:5]1[NH:9][C:10]1[N:14]([CH:15]([CH3:17])[CH3:16])[N:13]=[C:12]([CH3:18])[CH:11]=1)(=O)C.Cl>CO>[CH:15]([N:14]1[C:10]([NH:9][C:5]2[NH:6][CH2:7][CH2:8][N:4]=2)=[CH:11][C:12]([CH3:18])=[N:13]1)([CH3:17])[CH3:16]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 127637891-Acetyl-2-(1-isopropyl-3-methyl-5-pyrazolyl) amino-2-imidazoline

Product 1

HCID 127638112-(1-Isopropyl-3-methyl-5-pyrazolyl) amino-2-imidazolineYield 77.8%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1-acetyl-2-(1-isopropyl-3-methyl-5-pyrazolyl) amino-2-imidazoline (14.0 g.) was treated with HCl in methanol as described in Example II to give 9.05 g of product, mp 173°-175° C.

Sources & evidence

ORD record
ord-c6ca815c114f444fa1aec5c7624ae373
Source dataset
uspto-grants-1980_11
Patent number
US04234594

Reaction notes

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