2-Amino-2-methyl-1-propanol → HCID 14700381, compound

HRID 2248087Notes

Reaction equation

HRID 2248087 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[NH2:15][C:16](C)([CH3:19])[CH2:17][OH:18]>>[N+:12]([C:3]1[CH:4]=[N:5][C:6]2[C:11]([C:2]=1[NH:15][CH:16]([CH3:19])[CH2:17][OH:18])=[CH:10][CH:9]=[CH:8][CH:7]=2)([O-:14])=[O:13]

Participants

3

Reactant 2

HCID 118072-Amino-2-methyl-1-propanolHCID 112758084-Chloro-3-nitroquinoline

Product 1

HCID 14700381HCID 14700381, compound

Procedure

Using the method of Example 1, 4-chloro-3-nitroquinoline was reacted with 2-amino-2-methyl-1-propanol to afford 2-[(3-nitro-4-quinolinyl)amino]-1-propanol, m.p. 207°-211° C. Analysis: Calculated for C12H13N3O3 : %C, 58.3; %H, 5.3; %N,17; Found: %C, 58.6; %H, 5.3; %N, 17.2.

Sources & evidence

ORD record
ord-af5606095d244d29a4cfeb20f752b369
Source dataset
uspto-grants-1991_08
Patent number
US05037986

Reaction notes

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