Ammonia → HCID 178508172, compound

Participants

Reaction Steps

Using the method of Example 18, the product of Example 30, 0.2g (0.0010 mole) of 4-chloro-1H-imidazo[4,5-c]quinoline was aminated at 175 ° C. in 12% ammonia in methanol to provide 1H-imidazo[4,5-c]quinolin-4-amine. The structure was verified by comparison of infrared and nuclear magnetic resonance spectra of the product with spectra of the product from Example 32 below.

Provenance & Evidence