Benzoyl isothiocyanate → N-(1,3-Diphenyl-1H-pyrazol-5-yl)thiourea

HRID 224811Notes

Reaction equation

HRID 224811 reaction equation
[C:1]1([N:7]2[C:11]([NH2:12])=[CH:10][C:9]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C([N:27]=[C:28]=[S:29])(=O)C1C=CC=CC=1>>[C:1]1([N:7]2[C:11]([NH:12][C:28]([NH2:27])=[S:29])=[CH:10][C:9]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[N:8]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 68284Benzoyl isothiocyanateHCID 1999691,3-Diphenyl-1H-pyrazol-5-amine

Product 1

HCID 12763850N-(1,3-Diphenyl-1H-pyrazol-5-yl)thiourea

Procedure

1,3-Diphenyl-5-amino pyrazole (117.5 g.) and benzoyl isothiocyanate (89.65 g.) were reacted as described in Example IV to give 119.8 g. of product, mp 198°-201° C.

Workup

  1. customto give 119.8 g

Sources & evidence

ORD record
ord-cc62d294056349a6869a285b0e3793ba
Source dataset
uspto-grants-1980_11
Patent number
US04234594

Reaction notes

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