Hydrochloric Acid → 2[1-(4-Fluorophenyl)-3-methyl-5-pyrazolyl] amino-2-imidazoline

HRID 224830Notes

Reaction equation

HRID 224830 reaction equation
C([N:4]1[CH2:8][CH2:7][N:6]=[C:5]1[NH:9][C:10]1[N:14]([C:15]2[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=2)[N:13]=[C:12]([CH3:22])[CH:11]=1)(=O)C.Cl>CO>[F:21][C:18]1[CH:17]=[CH:16][C:15]([N:14]2[C:10]([NH:9][C:5]3[NH:6][CH2:7][CH2:8][N:4]=3)=[CH:11][C:12]([CH3:22])=[N:13]2)=[CH:20][CH:19]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 127637961-Acetyl-2[1-(4-fluorophenyl)-3-methyl-5-pyrazolyl] amino-2-imidazoline

Product 1

HCID 127638182[1-(4-Fluorophenyl)-3-methyl-5-pyrazolyl] amino-2-imidazoline

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1-Acetyl-2[1-(4-fluorophenyl)-3-methyl-5-pyrazolyl] amino-2-imidazoline (21.0 g.) was treated with HCl in methanol as described in Example II to give 7.503 g. mp 213°-215°

Workup

  1. customto give 7.503 g

Sources & evidence

ORD record
ord-091c2fbd75b14686b57dc68aa92712dd
Source dataset
uspto-grants-1980_11
Patent number
US04234594

Reaction notes

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