反应详情

温度

40 °C

A mixture of 245 parts of α-(4-chlorophenyl)-1-methyl-1H-benzotriazole-6-methanol and 1500 parts of a hydrobromic acid solution in acetic acid was stirred for 2.5 hours at 40° C. The reaction mixture was evaporated at 60° C. and the residue was stirred in dichloromethane. After cooling to 10° C., the precipitated product was filtered off and dried, yielding 285 parts (76.6%) of 6-[bromo(4-chlorophenyl)methyl]-1-methyl-1H-benzotriazole monohydrobromide (int. 130).

1. customThe reaction mixture was evaporated at 60° C.
2. stirringthe residue was stirred in dichloromethane
3. temperatureAfter cooling to 10° C.
4. filtrationthe precipitated product was filtered off
5. customdried