Hydrochloric Acid → 2-[1-(3-Trifluoromethylphenyl)-5-pyrazolyl] amino-2-imidazoline hydrochloride

HRID 224839Notes

Reaction equation

HRID 224839 reaction equation
C([N:4]1[CH2:8][CH2:7][N:6]=[C:5]1[NH:9][C:10]1[N:14]([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([C:21]([F:24])([F:23])[F:22])[CH:16]=2)[N:13]=[CH:12][CH:11]=1)(=O)C.[ClH:25]>CO>[ClH:25].[F:24][C:21]([F:22])([F:23])[C:17]1[CH:16]=[C:15]([N:14]2[C:10]([NH:9][C:5]3[NH:6][CH2:7][CH2:8][N:4]=3)=[CH:11][CH:12]=[N:13]2)[CH:20]=[CH:19][CH:18]=1

Participants

4

Reactant 2

HCID 313Hydrochloric Acid2×HCID 570896611-Acetyl-2-[1-(3-Trifluoromethylphenyl)-5-pyrazolyl] amino-2-imidazoline

Product 1

HCID 705917982-[1-(3-Trifluoromethylphenyl)-5-pyrazolyl] amino-2-imidazoline hydrochloride

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1-Acetyl-2-[1-(3-Trifluoromethylphenyl)-5-pyrazolyl] amino-2-imidazoline (14.5 g.) was treated with HCl in methanol as described in Example II to give 10.69 g. product as the HCl salt, mp 151°-153°.

Workup

  1. customto give 10.69 g

Sources & evidence

ORD record
ord-a6df69ae88f1489aa5ffdfed3e95dd02
Source dataset
uspto-grants-1980_11
Patent number
US04234594

Reaction notes

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