Hydrochloric Acid → 2-[1(4-chloro-2-methylphenyl)-3-methyl-5-pyrazolyl] amino-2-imidazoline HCl

HRID 224843Notes

Reaction equation

HRID 224843 reaction equation
C([N:4]1[CH2:8][CH2:7][N:6]=[C:5]1[NH:9][C:10]1[N:14]([C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][C:16]=2[CH3:22])[N:13]=[C:12]([CH3:23])[CH:11]=1)(=O)C.Cl>CO>[ClH:21].[Cl:21][C:18]1[CH:19]=[CH:20][C:15]([N:14]2[C:10]([NH:9][C:5]3[NH:6][CH2:7][CH2:8][N:4]=3)=[CH:11][C:12]([CH3:23])=[N:13]2)=[C:16]([CH3:22])[CH:17]=1

Participants

4

Reactant 2

HCID 313Hydrochloric Acid2×HCID 127638021-Acetyl-2[1(4-chloro-2-methylphenyl)-3-methyl-5-pyrazolyl] amino-2-imidazoline

Product 1

HCID 867373392-[1(4-chloro-2-methylphenyl)-3-methyl-5-pyrazolyl] amino-2-imidazoline HCl

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1-Acetyl-2[1-(4-chloro-2-methylphenyl)-3-methyl-5-pyrazolyl] amino-2-imidazoline (10.0 g.) was treated with HCl in methanol as described in Example II to give 7.4 g. product as the HCl salt, mp 134°-135°.

Workup

  1. customto give 7.4 g

Sources & evidence

ORD record
ord-2c0a18c550f64422a9a52d6e17d5b559
Source dataset
uspto-grants-1980_11
Patent number
US04234594

Reaction notes

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