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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2248475Generated: November 2, 2026

Dimethylformamide → HCID 14988296, compound

https://huagongshe.com/reaction/2248475

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantPotassium HydroxideHCID 14797—
ReactantIndole-3-acetonitrileHCID 351795—
ProductHCID 14988296HCID 14988296—

Reaction Steps

To a cold solution of 3-cyanomethyl-1H-indole (25 g) in 200 ml dimethylformamide (DMF), was added milled KOH (48 g) portionwise maintaining the temperature at 0° to 5° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05039811
Source datasetuspto-grants-1991_08
ORD IDord-8d8919e7b75444b188e424f2ce482674
Source noteuspto-grants-1991_08