4-Chloro-3-nitropyridine → N-(3-Nitro-4-pyridinyl)-N-propyl-1H-indol-1-amine

HRID 2248479Notes

Reaction equation

HRID 2248479 reaction equation
[CH2:1]([NH:4][N:5]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=[CH:6]1)[CH2:2][CH3:3].Cl[C:15]1[CH:20]=[CH:19][N:18]=[CH:17][C:16]=1[N+:21]([O-:23])=[O:22]>CN1CCCC1=O>[N+:21]([C:16]1[CH:17]=[N:18][CH:19]=[CH:20][C:15]=1[N:4]([CH2:1][CH2:2][CH3:3])[N:5]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=[CH:6]1)([O-:23])=[O:22]

Participants

4

Reactant 2

HCID 27357814-Chloro-3-nitropyridineHCID 107023901H-Indol-1-amine, N-propyl-

Product 1

HCID 14988270N-(3-Nitro-4-pyridinyl)-N-propyl-1H-indol-1-amine

Reagents, catalysts & solvents 1

HCID 13387N-methyl-2-pyrrolidoneSolvent

Procedure

The title compound was prepared from N-propyl-1H-indol-1-amine and 4-chloro-3-nitropyridine in 1-methyl-2-pyrrolidinone at 100° C. for 4 hours in substantially the same manner as in Example 1, m.p. 84°-86° C.

Sources & evidence

ORD record
ord-92adf0ee3f6b4895b499c6f113937943
Source dataset
uspto-grants-1991_08
Patent number
US05039811

Reaction notes

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