1-Aminoindole → HCID 19072368, compound

HRID 2248480Notes

Reaction equation

HRID 2248480 reaction equation
[N:1]1([NH2:10])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.Cl.[Cl:12][C:13]1[CH:18]=[CH:17][N:16]=[CH:15][C:14]=1[F:19]>C(O)(C)C>[ClH:12].[F:19][C:14]1[CH:15]=[N:16][CH:17]=[CH:18][C:13]=1[NH:10][N:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1

Participants

4

Reactant 2

HCID 6432211-AminoindoleHCID 193602344-Chloro-3-fluoropyridine hydrochloride

Product 1

HCID 19072368HCID 19072368, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

The title compound was prepared from 1H-indol-1-amine and 4-chloro-3-fluoropyridine hydrochloride in isopropanol at 90° C. for 4 hours in substantially the same manner as in Example 1, m.p. >250° C.

Sources & evidence

ORD record
ord-40020d6a8b104fd793591694015fe758
Source dataset
uspto-grants-1991_08
Patent number
US05039811

Reaction notes

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