HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-1H-indol-1-amine → N-(3-Fluoro-4-pyridinyl)-2-methyl-1H-indol-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-1H-indol-1-amine | HCID 12427291 | — |
| Reactant | 4-Chloro-3-fluoropyridine hydrochloride | HCID 19360234 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | N-(3-Fluoro-4-pyridinyl)-2-methyl-1H-indol-1-amine | HCID 14988279 | — |
Reaction Steps
The title compound was prepared from 2-methyl-1H-indol-1-amine and 4-chloro-3-fluoropyridine hydrochloride in 1-methyl-2-pyrrolidone for 1 hour in substantially the same manner as in Example 1, m.p. 157°-158° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05039811 |
| Source dataset | uspto-grants-1991_08 |
| ORD ID | ord-b998a7cb9d344ea7b76e211a4322dc7e |
| Source note | uspto-grants-1991_08 |