1-Bromopropane → HCID 14988290, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[NH:8][N:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11]([CH3:18])=[CH:10]1.Br[CH2:20][CH2:21][CH3:22].[H-].[Na+]>>[Cl:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[N:8]([CH2:20][CH2:21][CH3:22])[N:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11]([CH3:18])=[CH:10]1Participants
4
Procedure
The title compound was prepared from N-(3-chloro-4-pyridinyl)-3-methyl-1H-indol-1-amine and 1-bromopropane with the aid of NaH in substantially the same manner as in Example 4, m.p. 68°-70°.
Sources & evidence
- ORD record
- ord-cf863d23af874abda24d2a1bbf6293f5
- Source dataset
- uspto-grants-1991_08
- Patent number
- US05039811
Reaction notes
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