HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-((1,1-dimethylethoxy)carbonyl)-beta-alanine → 5-[3-(1-t-Butoxyformamido)propionamido]-2-nitrobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-((1,1-dimethylethoxy)carbonyl)-beta-alanine | HCID 76809 | — |
| Reactant | 5-Amino-2-nitrobenzoic acid | HCID 83298 | — |
| Reactant | N-[5-[3-(1-t-butoxyformamido)propionamido]-2-nitrobenzoyl]-beta-alanine t-butyl ester | HCID 19996354 | — |
| Product | 5-[3-(1-t-Butoxyformamido)propionamido]-2-nitrobenzoic acid | HCID 54030903 | — |
Reaction Steps
For the preparation of the ester starting material, N-(t-butoxycarbonyl)-β-alanine and 5-amino-2-nitrobenzoic acid are coupled to give 5-[3-(1-t-butoxyformamido)propionamido]-2-nitrobenzoic acid, MS: 354 (17, M+H), and the latter is reacted with β-alanine t-butyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05039805 |
| Source dataset | uspto-grants-1991_08 |
| ORD ID | ord-101212eaaf064c6bb391393669452fad |
| Source note | uspto-grants-1991_08 |