HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminobenzoic Acid → HCID 10423016, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminobenzoic Acid | HCID 7419 | — |
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | 4-Cyanobenzoic acid | HCID 12087 | — |
| Reactant | 2-Chloro-4,6-dimethoxy-1,3,5-triazine | HCID 18450 | — |
| Solvent | dichloromethane N,N-dimethylformamide | HCID 22350042 | — |
| Product | HCID 10423016 | HCID 10423016 | 70% |
Reaction Steps
4-Cyanobenzoic acid is activated with 2-chloro-4,6-dimethoxy-1,3,5-triazine and N-methylmorpholine analogously to Example 1 and subsequently reacted with 3-aminobenzoic acid in DMF/CH2Cl2. There is obtained m-(p-cyanobenzamido)benzoic acid in the form of colourless crystals. Yield: 70%, m.p. 267° C. (ethyl acetate/acetonitrile).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05039805 |
| Source dataset | uspto-grants-1991_08 |
| ORD ID | ord-4a871c865f0f4bdb9e83fb4acfc81f51 |
| Source note | uspto-grants-1991_08 |