Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 224864Generated: October 25, 2026

Dimethyl(methylene)ammounium iodide → 2-[2-(5-Dimethylaminomethyl-2-thienylmethylthio)ethylamino]-5-(3-pyridylmethyl)-4-pyrimidone

https://huagongshe.com/reaction/224864

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl(methylene)ammounium iodideHCID 2724133—
Reactant2-[2-(2-Thienylmethylthio)ethylamino]-5-(3-pyridylmethyl)-4-pyrimidoneHCID 13505296—
SolventDimethylformamideHCID 6228—
Product2-[2-(5-Dimethylaminomethyl-2-thienylmethylthio)ethylamino]-5-(3-pyridylmethyl)-4-pyrimidoneHCID 13505300—

Reaction Steps

2-[2-(2-Thienylmethylthio)ethylamino]-5-(3-pyridylmethyl)-4-pyrimidone is reacted with an excess of dimethyl(methylene)ammonium iodide in dimethylformamide at room temperature to give 2-[2-(5-dimethylaminomethyl-2-thienylmethylthio)ethylamino]-5-(3-pyridylmethyl)-4-pyrimidone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04234588
Source datasetuspto-grants-1980_11
ORD IDord-485ed5ab69184a229d9298969b4bd43c
Source noteuspto-grants-1980_11