HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → Methyl 3-hydroxy-5-mercapto-4-methylthiphene-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Thiophene-2-thiol, S-acetyl- | HCID 13133366 | — |
| Reactant | Methyl 5-acetylthio-3-hydroxy-4-methylthiophene-2-carboxylate | HCID 54710754 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 3-hydroxy-5-mercapto-4-methylthiphene-2-carboxylate | HCID 54684845 | — |
Reaction Steps
The acetylthiothiophene of (f) above (10 mmol) was added to 30 ml of 1M potassium hydroxide in methanol. After acidification of the mixture, the mercapto thiophene was obtained, recrystallising from hexane, m.p. 86°-88° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05041461 |
| Source dataset | uspto-grants-1991_08 |
| ORD ID | ord-7076ab0dd12c417cb940f3f574dd7eb8 |
| Source note | uspto-grants-1991_08 |