Sodium Carbonate → HCID 10107780, compound

Participants

Reaction Steps

A mixture of (E)-3-(7-chloro-2-quinolinylethenyl)phenyl acetate (7.4 g, 22.9 mmol) and anhydrous sodium carbonate (606 mg, 5.7 mmol) in 135 ml of methanol is stirred at room temperature for 36 hours. pH 7 buffer (250 ml) is added and the precipitated solid filtered and dried to afford (E)-3-(7-chloro-2-quinolinylethenyl)phenol which is used directly in the next step.

Provenance & Evidence