Hydrochloric Acid → HCID 14093658, compound

HRID 2248921Notes

Reaction equation

HRID 2248921 reaction equation
[Na].[C:2]([CH2:5][NH:6][C@H:7]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C@H:8]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[OH:9])([OH:4])=[O:3].Cl>O>[C:2]([CH2:5][NH:6][C@H:7]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C@H:8]([C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)[OH:9])([OH:4])=[O:3]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 70371753HCID 70371753, compound

Product 1

HCID 14093658HCID 14093658, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

1.55 g of (1S,2R)-2-carboxymethylamino-1,2-diphenylethanol mono sodium salt was dissolved in 40 ml of water and 1.2M hydrochloric acid was added to adjust the pH at 8. The precipitated crystals were washed 2 times with water and 2 times with methanol. The washed crystals were dried under reduced pressure (about 2 mm Hg) at 70° C. for 12 h. Mp 250°-251.5° C. (decomp.); [α]D21 -3.4° (c 1.00, 1H NaOH). IR (KBr): 3320, 3050, 2890, 1625, 1570, 1390, 760, 710, 700 cm-1.

Workup

  1. washThe precipitated crystals were washed 2 times with water and 2 times with methanol
  2. customThe washed crystals were dried under reduced pressure (about 2 mm Hg) at 70° C. for 12 h

Sources & evidence

ORD record
ord-ba4a8f6e69e64968b73f644d302c24e4
Source dataset
uspto-grants-1991_08
Patent number
US05041573

Reaction notes

Loading…