反应详情

Trans-N-[(2R)-2-phenylpropanoyl-3-amino-1,2,3,4-tetrahydro-2-naphthalenol, diastereoisomer A (183 mg) was refluxed in 6N aqueous hydrochloric acid (20 ml) for 4 hours. The reaction mixture was evaporated in vacuo and the residue taken up in water. The aqueous solution was washed with ethyl acetate and evaporated to give a white solid which was recrystallized from a methanol/ethyl acetate mixture to yield the title compound (99 mg).

1. customThe reaction mixture was evaporated in vacuo
2. washThe aqueous solution was washed with ethyl acetate
3. customevaporated
4. customto give a white solid which
5. customwas recrystallized from a methanol/ethyl acetate mixture