Benzaldehyde → HCID 19994129, compound

Participants

Reaction Steps

A reaction vessel equipped with a thermometer, a dropping funnel, a stirrer and a condenser having a water separator was charged with 133 g of diisopropanolamine and 100 g of benzene, to which 107 g of benzaldehyde was added dropwise at room temperature for one hour. The content was heated to reflux and, after removing water produced during reacting, reacted for another 5 hours. Benzene was removed under a reduced pressure and then distilled at 125° to 127° C./1 mmHg to obtain 214 g of 2-phenyl-3-(2-hydroxypropyl)-5-methyloxazolidine.

Provenance & Evidence