Dinitrofluorobenzene → HCID 14882421, compound

HRID 2249261Notes

Reaction equation

HRID 2249261 reaction equation
C(N(CC)CC)C.[Br:8][C:9]1[NH:10][C:11]([CH3:20])=[C:12]([C:14]([O:16][CH:17]([CH3:19])[CH3:18])=[O:15])[N:13]=1.F[C:22]1[CH:27]=[CH:26][C:25]([N+:28]([O-:30])=[O:29])=[CH:24][C:23]=1[N+:31]([O-:33])=[O:32]>C1(C)C=CC=CC=1>[N+:28]([C:25]1[CH:24]=[C:23]([N+:31]([O-:33])=[O:32])[CH:22]=[CH:27][C:26]=1[N:10]1[C:11]([CH3:20])=[C:12]([C:14]([O:16][CH:17]([CH3:18])[CH3:19])=[O:15])[N:13]=[C:9]1[Br:8])([O-:30])=[O:29]

Participants

5

Reactant 3

HCID 6264DinitrofluorobenzeneHCID 8471TriethylamineHCID 13566327HCID 13566327, compound

Product 1

HCID 14882421HCID 14882421, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

4.2 ml of triethylamine was added dropwise to 5 g (0.02 mol) of isopropyl 2-bromo-5-methyl-4-imidazolecarboxylate, 3.9 g of 1-fluoro-2,4-dinitrobenzene and 200 ml of toluene, and the mixture was refluxed for 16 hours. The toluene solution was then washed with water, dried and concentrated. The residue was stirred with diethyl ether and the solid obtained in this manner was isolated.

Workup

  1. temperaturethe mixture was refluxed for 16 hours
  2. washThe toluene solution was then washed with water
  3. customdried
  4. concentrationconcentrated
  5. customthe solid obtained in this manner
  6. customwas isolated

Sources & evidence

ORD record
ord-338e3c5828304ce682b66048e63b5773
Source dataset
uspto-grants-1991_08
Patent number
US05043454

Reaction notes

Loading…