HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenyl isocyanate → 3-(1-Phenylcarbamoyloxytridecyl)-2-triethylsilylfuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenyl isocyanate | HCID 7672 | — |
| Reactant | 3-(1-Hydroxytridecyl)-2-triethylsilylfuran | HCID 19019907 | — |
| Catalyst | Copper | HCID 23978 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-(1-Phenylcarbamoyloxytridecyl)-2-triethylsilylfuran | HCID 19019896 | — |
Reaction Steps
3-(1-Hydroxytridecyl)-2-triethylsilylfuran (Compound 20) is reacted with phenyl isocyanate and copper (2) chloride in dimethylformamide to give 3-(1-phenylcarbamoyloxytridecyl)-2-triethylsilylfuran (Compound 21). Oxidizing the intermediate with singlet oxygen, under similar conditions as in Example 1, and thereafter reduction with sodium borohydride gives 3-(1-phenylcarbamoyloxytridecyl)-2(5H)-furanone (Compound 8).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05043457 |
| Source dataset | uspto-grants-1991_08 |
| ORD ID | ord-85c15dd3b1f049fdac28a320c290f60a |
| Source note | uspto-grants-1991_08 |