反应详情

3-(1-Hydroxytridecyl)-2-triethylsilylfuran (Compound 20) is reacted with phenyl isocyanate and copper (2) chloride in dimethylformamide to give 3-(1-phenylcarbamoyloxytridecyl)-2-triethylsilylfuran (Compound 21). Oxidizing the intermediate with singlet oxygen, under similar conditions as in Example 1, and thereafter reduction with sodium borohydride gives 3-(1-phenylcarbamoyloxytridecyl)-2(5H)-furanone (Compound 8).