反应详情

Reducing 3-(1-azidotridecyl)-2-triethylsilylfuran (Compound 24 with lithium aluminum hydride, as in Example 8, followed by reacting the intermediate with methanesulfonyl chloride, gives 3-(1-methanesulfonamidotridecyl)-2-triethylsilylfuran (Compound 26). Oxidizing this sulfonamide, under conditions as in Example 1, followed by reduction with sodium borohydride gives 3-(1-methanesulfonamidotridecyl)-2(5H)-furanone (Compound 11).