HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Chlorophenyl)propyl methanesulfonate → 4-carboxy-2-[3-(4-chlorophenyl)propyl]-6-(2,3-dihydro-1-benzofuran-5-yl)-2H-pyridazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Chlorophenyl)propyl methanesulfonate | HCID 13079705 | — |
| Reactant | HCID 23094117 | HCID 23094117 | — |
| Reactant | 2-[3-(2-chlorophenyl)propyl]-6-(2,3-dihydro-1-benzofuran-5-yl)-4-methanesulfonyloxymethyl-2H-pyridazin-3-one | HCID 23094118 | — |
| Product | 4-carboxy-2-[3-(4-chlorophenyl)propyl]-6-(2,3-dihydro-1-benzofuran-5-yl)-2H-pyridazin-3-one | HCID 23094134 | 71% |
Reaction Steps
The general procedure of Example 1 (3) was carried out by use of 6-(2,3-dihydro-1-benzofuran-5-yl)-4-methoxycarbonyl-2H-pyridazin-3-one and 3-(4-chlorophenyl)-1-propanol methanesulfonate, to thereby yield the title compound as a yellow powder (yield: 71.0%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07314877B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-14dea6e2d62f4aa683f9f9746ed6a4c8 |
| Source note | uspto-grants-2008_01 |