HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 2-Methoxycarbonylaminohexanoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Methyl 2-chlorohexanoate | HCID 85786 | — |
| Reactant | Potassium cyanate | HCID 11378442 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Methoxycarbonylaminohexanoic acid methyl ester | HCID 53655761 | 67% |
Reaction Steps
11.52 grams of 2-chlorohexanoic acid methyl ester were heated with 8.52 grams of potassium cyanate and 7.85 grams of methanol in 70 ml of DMF. After a reaction time of 30 hours the reaction mixture was worked up as described in Example 1. There were obtained 9.53 grams (67%) of 2-methoxycarbonylaminohexanoic acid methyl ester with a purity of 99% (determined gas chromatographically).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04234744 |
| Source dataset | uspto-grants-1980_11 |
| ORD ID | ord-504dd33590194b8ea0bde7260b19dc3c |
| Source note | uspto-grants-1980_11 |