2-Chlorobenzothiazole → HCID 22563261, compound

HRID 2249602Notes

Reaction equation

HRID 2249602 reaction equation
Cl[C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[NH2:11][CH2:12][C:13]([NH2:16])([CH3:15])[CH3:14]>N1C=CC=CC=1>[S:3]1[C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=[C:2]1[NH:11][CH2:12][C:13]([CH3:15])([NH2:16])[CH3:14]

Participants

4

Reactant 2

HCID 119872-ChlorobenzothiazoleHCID 131282-Methylpropylenediamine

Product 1

HCID 22563261HCID 22563261, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

A solution of 2-chlorobenzothiazole (5.0 g) in 1,2-diamino-2-methylpropane (20 ml) and pyridine (2.3 ml) was stirred 2 h at RT. The solvent was evaporated. Flash chromatography (silica gel; CH2Cl2/MeOH) provided 6.2 g of a colorless oil, which crystallized upon standing.

Workup

  1. customThe solvent was evaporated

Sources & evidence

ORD record
ord-f3d39e1fa292406b9cde6341e15ccf91
Source dataset
uspto-grants-2008_01
Patent number
US07314884B2

Reaction notes

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