Creatine → HCID 23697890, compound

HRID 2249913Notes

Reaction equation

HRID 2249913 reaction equation
[O:1]=[C:2]([CH2:4][N:5]([C:7](=[NH:9])[NH2:8])[CH3:6])[OH:3].[OH-].[Na+:11]>O>[CH3:6][N:5]([CH2:4][C:2]([O-:3])=[O:1])[C:7]([NH2:9])=[NH:8].[Na+:11]

Participants

4

Reactant 2

HCID 586CreatineHCID 14798Sodium Hydroxide

Product 1

HCID 23697890HCID 23697890, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Separately, in a single-necked, round bottomed flask, equipped with a magnetic stirrer, 6.56 g (50 mmol) of creatine is dissolved in 500 ml of water. To this is added 55 ml of 1M sodium hydroxide with vigorous stirring, until heat production ceases. At this point the water is removed by evaporation to yield the carboxylate salt, sodium 2-(1-methylguanidino)acetate, shown below.

Workup

  1. customSeparately, in a single-necked, round bottomed flask, equipped with a magnetic stirrer
  2. temperatureuntil heat production ceases
  3. customAt this point the water is removed by evaporation

Sources & evidence

ORD record
ord-c785c1dce8da4c73b364a81cc720fceb
Source dataset
uspto-grants-2008_01
Patent number
US07314945B1

Reaction notes

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