HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59640494, compound → HCID 59640425, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59640494 | HCID 59640494 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 59640425 | HCID 59640425 | — |
Reaction Steps
{1-[4-(3-Piperidin-1-yl-propoxy)-phenyl]-cyclopropyl}-carbamic acid benzyl ester (1.08 g, 2.65 mmol) is dissolved in ethanol (50 mL), and 10% Pd/C is added (200 mg). The mixture was stirred under a balloon on hydrogen for 3 hours. The reaction mixture was stirred through a plug of silica gel to give the desired compound. HRMS 275.2123 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07314937B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-59a363fdde464ddca3c0c95936774d25 |
| Source note | uspto-grants-2008_01 |