Hydrochloric Acid → HCID 178428716, compound

Participants

Reaction Steps

31 mg of 2-[2-(2-Amino-4-methylpyridin-6-yl)ethyl]-3H-imidazo[4,5-b]pyridine (compound1) are dissolved in 16 ml of dichloromethane. Under ice-cooling, 61 μl of a solution of hydrochloric acid in diethylether (2M strength) are added. The mixture is evaporated to dryness and the residue lyophillized from 15 ml water to give 35 mg of the title compound as colorless lyophilisate. M.p. 136° C. MS: 254.2 (MH+), 528.8 (2MNa+).

Provenance & Evidence