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HRID2250558

反应详情

EQUATION

反应方程式

HRID 2250558 的结构方程式

REACTANTS

反应物

1
结构：CCOC(=O)CCCCCC(C(C)=O)(C(C)=O)C(=O)c1ccc(C#N)cc1
HCID57444529

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)CCCCCC(C(C)=O)C(=O)c1ccc(C#N)cc1
HCID57444530

未命名化合物

收率 72.5%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O=C(O)C(F)(F)F
溶剂HCID6422

未命名化合物

CONDITIONS

反应条件

温度
20 °C

PROCEDURE

实验过程

Ethyl 7-acetyl-7-(4-cyanobenzoyl)-8-oxononanoate (3.5 g) was dissolved in trifluoroacetic acid (12.6 ml) and the mixture was stirred at 20° C. for 15 minutes. The mixture was partitioned between ethyl acetate and water. The organic layer was separated, washed with water, aqueous sodium bicarbonate and brine, dried over MgSO4 (magnesium sulfate), and evaporated to give ethyl 7-(4-cyanobenzoyl)-8-oxononanoate (2.25 g) as an oil.

WORKUP

后处理

  1. customThe mixture was partitioned between ethyl acetate and water
  2. customThe organic layer was separated
  3. washwashed with water, aqueous sodium bicarbonate and brine
  4. dry with materialdried over MgSO4 (magnesium sulfate)
  5. customevaporated