Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2250651Generated: October 31, 2026

HCID 68802434, compound → HCID 69309153, compound

https://huagongshe.com/reaction/2250651

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68802434HCID 68802434—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 69309153HCID 6930915392.8%

Reaction Steps

A solution of 5-[7-ethyl-2-methyl-4-(2-vinyl-4-pyridinyl)pyrrolo[1,2-b]pyridazin-3-yl]pentanoic acid (15 mg) in MeOH was added 10% Pd/C (2 mg). The mixture was stirred under hydrogen atomosphere (1 atm) for 6 h. The reaction mixture was filtered through Celite and the filtrate was concentrated in vacuo. The residue was triturated with hexane to give 5-[7-ethyl-4-(2-ethyl-4-pyridinyl)-2-methylpyrrolo[1,2-b]pyridazin-3-yl]pentanoic acid (14 mg) as an yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07317009B2
Source datasetuspto-grants-2008_01
ORD IDord-c1730118b14d4c6e8e897ddcef566eec
Source noteuspto-grants-2008_01