Potassium Nitrate → 5-Bromo-2-nitrobenzaldehyde

Participants

Reaction Conditions

Reaction Steps

3-Bromobenzaldehyde (18.5 g, 100 mmol) was added dropwise to a solution of potassium nitrate (20.2 g, 200 mmol) in concentrated sulfuric acid (100 mL) cooled to 0° C. by an ice water bath. The solution was stirred for an additional 15 minutes upon complete addition of 3-bromobenzaldehyde whereupon the entire reaction mixture was added to ice (250 g). The precipitate was isolated by filtration, and the solid was washed with de-ionized water until the pH of the wash was neutral. Drying for 12 hours under vacuum gave the yellow solid, 5-bromo-2-nitrobenzaldehyde was (11.8 g, 51% yield).

Provenance & Evidence