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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251119Generated: November 3, 2026

2-Methylpyrrolidine → 8-{4-[3-(2-Methyl-pyrrolidin-1-yl)-propoxy]-phenyl}-6,7-dihydro-5H-1,4,8a-triaza-s-indacene

https://huagongshe.com/reaction/2251119

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethylpyrrolidineHCID 13003—
Reactant10-{4-[3-(2-methyl-pyrrolidin-1-yl)-propoxy]-phenyl}-6,7,8,9-tetrahydro-5H-1,4,10a-triaza-cyclohepta[f]indeneHCID 11611130—
Reactant8-[4-(3-Chloro-propoxy)-phenyl]-6,7-dihydro-5H-1,4,8a-triaza-s-indaceneHCID 69255812—
Product8-{4-[3-(2-Methyl-pyrrolidin-1-yl)-propoxy]-phenyl}-6,7-dihydro-5H-1,4,8a-triaza-s-indaceneHCID 11675228—

Reaction Steps

Using the method described for the preparation of 10-{4-[3-(2-methyl-pyrrolidin-1-yl)-propoxy]-phenyl}-6,7,8,9-tetrahydro-5H-1,4,10a-triaza-cyclohepta[f]indene, the reaction of 8-[4-(3-chloro-propoxy)-phenyl]-6,7-dihydro-5H-1,4,8a-triaza-s-indacene and 2-methyl-pyrrolidine provided the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07319103B2
Source datasetuspto-grants-2008_01
ORD IDord-615ae4b9557f4c34bf735e024931c905
Source noteuspto-grants-2008_01