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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251136Generated: November 3, 2026

2-Methylpyrrolidine → 8-{4-[3-(2-Methyl-pyrrolidin-1-yl)-propoxy]-phenyl}-5H,7H-6-oxa-1,4,8a-triaza-s-indacene

https://huagongshe.com/reaction/2251136

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethylpyrrolidineHCID 13003—
Reactant8-[4-(3-Chloro-propoxy)-phenyl]-5H,7H-6-oxa-1,4,8a-triaza-s-indaceneHCID 58587720—
Product8-{4-[3-(2-Methyl-pyrrolidin-1-yl)-propoxy]-phenyl}-5H,7H-6-oxa-1,4,8a-triaza-s-indaceneHCID 11574414—

Reaction Steps

Using the method described for the preparation of 10-{4-[3-(2-Methyl-pyrrolidin-1-yl)-propoxy]-phenyl}-6,7,8,9-tetrahydro-5H-1,4,10a-triaza-cyclohepta[t]indene, the reaction of 8-[4-(3-Chloro-propoxy)-phenyl]-5H,7H-6-oxa-1,4,8a-triaza-s-indacene and 2-methyl-pyrrolidine provided compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07319103B2
Source datasetuspto-grants-2008_01
ORD IDord-4db1fa0bbf6f43189c07de5f85ca1d51
Source noteuspto-grants-2008_01