N-(2-Aminoethyl)piperidine → HCID 69276947, compound

HRID 2251144Notes

Reaction equation

HRID 2251144 reaction equation
[Cl:1][C:2]1[CH:22]=[CH:21][CH:20]=[CH:19][C:3]=1[CH2:4][N:5]1[C:13](=[O:14])[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:15]([OH:17])=O)[CH:11]=2)[C:6]1=[O:18].[N:23]1([CH2:29][CH2:30][NH2:31])[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1>>[Cl-:1].[Cl:1][C:2]1[CH:22]=[CH:21][CH:20]=[CH:19][C:3]=1[CH2:4][N:5]1[C:13](=[O:14])[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:15]([NH:31][CH2:30][CH2:29][NH+:23]3[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]3)=[O:17])[CH:11]=2)[C:6]1=[O:18]

Participants

3

Reactant 2

HCID 33944N-(2-Aminoethyl)piperidineHCID 2994323HCID 2994323, compound

Product 1

HCID 69276947HCID 69276947, compound

Procedure

2-(2-chloro-benzyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-carboxylic acid (100 mg, 0.316 mmol) and 2-piperidin-1-yl-ethylamine (113 μL, 0.792 mmol) were reacted with each other. Target compound in the amount of 131 mg (90%) was obtained by following the procedure described in Example 1.

Workup

  1. customTarget compound in the amount of 131 mg (90%) was obtained

Sources & evidence

ORD record
ord-7aa0e0ca26844700bf807c11f345db28
Source dataset
uspto-grants-2008_01
Patent number
US07319098B2

Reaction notes

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