2-Morpholinoethylamine → HCID 69277937, compound

HRID 2251153Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]([CH:20]=[CH:21][CH:22]=1)[CH2:5][N:6]1[C:14](=[O:15])[C:13]2[C:8](=[CH:9][CH:10]=[C:11]([C:16]([OH:18])=O)[CH:12]=2)[C:7]1=[O:19].[O:23]1[CH2:28][CH2:27][N:26]([CH2:29][CH2:30][NH2:31])[CH2:25][CH2:24]1>>[Cl-:1].[Cl:1][C:2]1[CH:3]=[C:4]([CH:20]=[CH:21][CH:22]=1)[CH2:5][N:6]1[C:14](=[O:15])[C:13]2[C:8](=[CH:9][CH:10]=[C:11]([C:16]([NH:31][CH2:30][CH2:29][NH+:26]3[CH2:27][CH2:28][O:23][CH2:24][CH2:25]3)=[O:18])[CH:12]=2)[C:7]1=[O:19]

Participants

Reactant 2

HCID 4082852-Morpholinoethylamine

HCID 69277800HCID 69277800, compound

Product 1

HCID 69277937HCID 69277937, compound

Procedure

2-(3-chloro-benzyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-carboxylic acid (100 mg, 0.316 mmol) and 2-morpholinoethane amine (103 μL, 0.792 mmol) were reacted with each other. Target compound in the amount of 59 mg (40%) was obtained by following the procedure described in Example 1.

Workup

customTarget compound in the amount of 59 mg (40%) was obtained

Sources & evidence

ORD record: ord-3c3c55e7c181442081545db56a285504
Source dataset: uspto-grants-2008_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07319098B2

Reaction notes

Loading…