Trifluoroacetic acid → 2-Methoxy-4-piperazin-1-yl-[1,3,5]triazine

HRID 2251216Notes

Reaction equation

HRID 2251216 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[N:19]=[C:18]([O:20][CH3:21])[N:17]=[CH:16][N:15]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.FC(F)(F)C(O)=O>>[CH3:21][O:20][C:18]1[N:19]=[C:14]([N:11]2[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]2)[N:15]=[CH:16][N:17]=1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 69038439HCID 69038439, compound

Product 1

HCID 690376682-Methoxy-4-piperazin-1-yl-[1,3,5]triazine

Procedure

Prepared in analogy to example 4.10 (c) from 4-(4-Methoxy-[1,3,5]triazin-2-yl)-piperazine-1-carboxylic acid tert-butyl ester and trifluoroacetic acid. MS (m/e): 196.4 (MH+, 100%)

Sources & evidence

ORD record
ord-deccef6fba1040e2bde52d69672ffe44
Source dataset
uspto-grants-2008_01
Patent number
US07319099B2

Reaction notes

Loading…