HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formic Acid → HCID 12883999, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formic Acid | HCID 284 | — |
| Reactant | Aniline | HCID 6115 | — |
| Reactant | HCID 12883998 | HCID 12883998 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 12883999 | HCID 12883999 | — |
Reaction Steps
A mixture of 100 g of 1-benzoyl-3-oxopyrrolidin-4-carboxylic acid ethyl ester, 42 ml of aniline and 23 ml of formic acid in 1.2 liters of ethanol is heated to reflux for 15 hours, concentrated by evaporation and the residue is crystallised from the ether/methylene chloride. 3-Anilino-1-benzoyl-2,5-dihydro-1H-pyrrol-4-carboxylic acid ethyl ester is obtained. M.P. 149°-151°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04235907 |
| Source dataset | uspto-grants-1980_11 |
| ORD ID | ord-ffd63da07fe543049483ca0e239ff43a |
| Source note | uspto-grants-1980_11 |