4-Methoxybenzaldehyde → [1-(4-{5-[(4-Methoxybenzylamino)methyl][1,2,4]oxadiazol-3-yl}phenyl)pyrrolidin-3-yl]dimethylamine

HRID 2251303Notes

Reaction equation

HRID 2251303 reaction equation
[NH2:1][CH2:2][C:3]1[O:7][N:6]=[C:5]([C:8]2[CH:13]=[CH:12][C:11]([N:14]3[CH2:18][CH2:17][CH:16]([N:19]([CH3:21])[CH3:20])[CH2:15]3)=[CH:10][CH:9]=2)[N:4]=1.[CH:22](=O)[C:23]1[CH:28]=[CH:27][C:26]([O:29][CH3:30])=[CH:25][CH:24]=1>>[CH3:30][O:29][C:26]1[CH:27]=[CH:28][C:23]([CH2:22][NH:1][CH2:2][C:3]2[O:7][N:6]=[C:5]([C:8]3[CH:9]=[CH:10][C:11]([N:14]4[CH2:18][CH2:17][CH:16]([N:19]([CH3:21])[CH3:20])[CH2:15]4)=[CH:12][CH:13]=3)[N:4]=2)=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 312444-MethoxybenzaldehydeHCID 68574687{1-[4-(5-Aminomethyl[1,2,4]oxadiazol-3-yl)phenyl)pyrrolidin-3-yl}dimethylamine

Product 1

HCID 59643613[1-(4-{5-[(4-Methoxybenzylamino)methyl][1,2,4]oxadiazol-3-yl}phenyl)pyrrolidin-3-yl]dimethylamine

Procedure

{1-[4-(5-aminomethyl[1,2,4]oxadiazol-3-yl)phenyl)pyrrolidin-3-yl}dimethylamine was reacted with p-anisaldehyde by method D. The product with the molecular weight of 407.23 (C23H29N5O2) was obtained in this way; MS (ESI): 408.30 (M+H+).

Workup

  1. customThe product with the molecular weight of 407.23 (C23H29N5O2) was obtained in this way

Sources & evidence

ORD record
ord-7710aec773174ce0b3c9723cef2b3372
Source dataset
uspto-grants-2008_01
Patent number
US07319108B2

Reaction notes

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