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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251304Generated: November 2, 2026

Potassium Carbonate → HCID 59643624, compound

https://huagongshe.com/reaction/2251304

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant4-Fluorobenzyl bromideHCID 68021—
ReactantHCID 68574706HCID 68574706—
SolventDimethylformamideHCID 6228—
ProductHCID 59643624HCID 59643624—

Reaction Conditions

Temperature60 °C

Reaction Steps

4-Fluorobenzyl bromide (18.9 mg) and potassium carbonate (27.6 mg) were added to a mixture of {3-[4-(3-dimethylaminopyrrolidin-1-yl)phenyl][1,2,4]oxadiazol-5-yl}methanol (28.8 mg) and DMF (0.3 ml). The reaction mixture was stirred at 60° C. for 3 h, filtered and purified by preparative HPLC. The product with the molecular weight of 396.20 (C22H25FN4O2) was obtained in this way; MS (ESI): 397.27 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07319108B2
Source datasetuspto-grants-2008_01
ORD IDord-740bffd8302248cc99fd09b89a5da476
Source noteuspto-grants-2008_01