HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 58755377, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 58755345 | HCID 58755345 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 58755377 | HCID 58755377 | — |
Reaction Steps
A solution of methyl 4-{[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl]methoxy}phenyl)amino]carbonyl}benzoate (10 mg, 17 μmol) in tetrahydrofuran (150 μL) was stirred vigorously with aqueous lithium hydroxide (104 μL, 0.5M) at ambient temperature for 24 h. The reaction was partitioned with ethyl acetate and then dried over anhydrous sodium sulfate, filtered, and was condensed to a residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07319109B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-b198d387dec54cce8f9549398324e98c |
| Source note | uspto-grants-2008_01 |