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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251325Generated: November 3, 2026

Lithium Hydroxide → HCID 58755377, compound

https://huagongshe.com/reaction/2251325

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantHCID 58755345HCID 58755345—
SolventTetrahydrofuranHCID 8028—
ProductHCID 58755377HCID 58755377—

Reaction Steps

A solution of methyl 4-{[(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl]methoxy}phenyl)amino]carbonyl}benzoate (10 mg, 17 μmol) in tetrahydrofuran (150 μL) was stirred vigorously with aqueous lithium hydroxide (104 μL, 0.5M) at ambient temperature for 24 h. The reaction was partitioned with ethyl acetate and then dried over anhydrous sodium sulfate, filtered, and was condensed to a residue.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07319109B2
Source datasetuspto-grants-2008_01
ORD IDord-b198d387dec54cce8f9549398324e98c
Source noteuspto-grants-2008_01